Defining genomic, transcriptomic, proteomic, epigenetic, and phenotypic biomarkers with prognostic capability in male breast cancer: a systematic review

S Chatterji, E Krzoska, CW Thoroughgood… - The Lancet …, 2023 - thelancet.com
… that male and female breast cancer differ in their molecular landscapes. In this systematic
review, we consolidated all existing prognostic biomarker data in male breast cancer spanning …

Increased ERBB2 Gene Copy Numbers Reveal a Subset of Salivary Duct Carcinomas with High Densities of Tumor Infiltrating Lymphocytes and PD-L1 Expression

K Chatzopoulos, AR Collins, S Sotiriou… - Head and Neck …, 2020 - Springer
… underlying gene copy number alterations and we evaluatedChromosome 17 copy numbers
that are detected by FISH can … in breast cancer patients, even without concurrent ERBB2

[HTML][HTML] Dual-color dual-hapten in situ hybridization (D-DISH)–Comparison with fluorescence in situ hybridization (FISH) for HER2/neu testing in breast cancer

PK Gajaria, S Tambe, T Pai, A Patil… - Indian Journal of …, 2020 - journals.lww.com
… SPEC ERBB2 probe specific for the chromosomal region … We evaluated the HER2/neu gene
amplification status by D-… the discrepancy in evaluating chromosome 17 abnormalities in our …

[HTML][HTML] ERBB2 FISH and Chromosome Microarray Testing of Gastroesophageal Adenocarcinomas at a Single Institution

A Yu, S Luikart, G Huang, S Han, J Zhao… - Cancer medicine …, 2020 - ncbi.nlm.nih.gov
… alone (eg, chromosome 17 ERBB2 gene locus), resulting in … most common abnormalities
in GEA and breast cancers, none … the value of CMA in GEA evaluation. Our study calls for the …

HER2 testing

RH Alvarez, J Cortés, M Falzon, M Gandy… - … agents in breast cancer, 2016 - Springer
… receptor 2 (HER2) ERBB2 gene has been at the forefront of … HER2 assessment in breast
cancer can be made using a variety of … by using alternative chromosome 17 reference genes: …

[PDF][PDF] … -2/neu gene Status by Chromogenic in Situ Hybridisation Assay on Borderline (2+) Immunohistochemistry Cases in Patients with Invasive Breast Carcinoma: An …

KF Khanam, T Chowdhury, SG Banu… - … Medical Research Council …, 2017 - bmrcbd.org
… diagnostic evaluation of HER2/neu status in breast cancer patients… been characterized by
many recurrent genetic abnormalities … ratio which is able to exclude chromosome 17 polysomy.…

[HTML][HTML] Breast cancer—epidemiology, classification, pathogenesis and treatment (review of literature)

B Smolarz, AZ Nowak, H Romanowicz - Cancers, 2022 - mdpi.com
gene, located on chromosome 17, is a suppressor gene that … of developing breast cancer
regardless of menopausal status. … These mutations, including NF1 loss and ERBB2 activating …

Genomic changes in normal breast tissue in women at normal risk or at high risk for breast cancer

DN Danforth Jr - Breast cancer: basic and clinical research, 2016 - journals.sagepub.com
… To characterize these abnormalities, a review of the literature has … as being at low risk for
breast cancer in this review. … for Her-2/neu (c-erbB2) protein overexpression. Rohan et al 83 …

[HTML][HTML] Recent advances of therapeutic targets based on the molecular signature in breast cancer: genetic mutations and implications for current treatment paradigms

ZS Lima, M Ghadamzadeh, FT Arashloo… - Journal of hematology & …, 2019 - Springer
… in breast cancer can be an effective therapeutic approach for developing novel drugs. This
systematic review discusses gene mutations linked to breast cancer, … status/quality of life [40]. …

[HTML][HTML] Prediction models for hormone receptor status in female breast cancer do not extend to males: further evidence of sex-based disparity in breast cancer

S Chatterji, JM Niehues, M van Treeck… - … Breast Cancer, 2023 - nature.com
… of BC, we evaluated the efficacy of attMIL pipelines in predicting ERα and PR status in both
… which could be predictive of the hormone receptor status of the tumor in H&E-stained slides. …